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Gilteritinib hemifumarate

SKU T71973-1 mg Category Small Compound Brand: TargetMol

Price range: 54 CAD through 728 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– Gilteritinib hemifumarate (ASP2215 hemifumarate) is a potent ATP-competitive dual FLT3 (IC50: 0.29 nM) and AXL (IC50: 0.73 nM) inhibitor for the treatment of relapsed or refractory FLT3 mutant AML.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T71973

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H44N8O3.1/2C4H4O4

References

– Yoko Ueno,et al. ASP2215, a novel FLT3/AXL inhibitor: Preclinical evaluation in combination with cytarabine and anthracycline in acute myeloid leukemia (AML).Journal of Clinical Oncology 2014 32:15_suppl, 7071

CAS Number

– 1254053-84-3

Molecular Weight

– C29H44N8O3.1/2C4H4O4

Compound Purity

– 0.9978

SMILES

– C(=C/C(O)=O)C(O)=O.N(C=1C(C(N)=O)=NC(CC)=C(NC2CCOCC2)N1)C3=CC(OC)=C(C=C3)N4CCC(CC4)N5CCN(C)CC5

Pathway

– Tyrosine Kinase/Adaptors|||Angiogenesis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.