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GIBH-130

SKU T4450-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 51 CAD through 248 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mL * 10 mM (in DMSO)10 mg 25 mg 5 mg

Clear

Products Details

Product Description

– GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T4450

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H20N6O

References

– Zhou W, Zhong G, Fu S, et al. Microglia-Based Phenotypic Screening Identifies a Novel Inhibitor of Neuroinflammation Effective in Alzheimer’s Disease Models[J]. Acs Chemical Neuroscience, 2016, 7(11):1499-1507.

CAS Number

– 1252608-59-5

Molecular Weight

– C20H20N6O

Compound Purity

– 0.9986

SMILES

– Cc1cc(nnc1C(=O)N1CCN(CC1)c1ncccn1)-c1ccccc1

Pathway

– Apoptosis|||Immunology/Inflammation

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.