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Fimepinostat
Price range: 62 CAD through 1,840 CAD
Products Details
Product Description
– Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan-histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon oral administration, CUDC-907 inhibits the activity of both PI3K class I isoforms and HDAC, thereby preventing the activation of the PI3K-AKT-mTOR signal transduction pathway that is often overactivated in many cancer cell types.
Web ID
– T2078
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H24N8O4S
Citations
– 1. Li M, Hu Y, Wang J, et al.The dual HDAC and PI3K inhibitor, CUDC‑907, inhibits tumor growth and stem‑like properties by suppressing PTX3 in neuroblastoma.International Journal of Oncology.2024, 64(2): 1-13.
References
– Qian C, et al. Cancer network disruption by a single molecule inhibitor targeting both histone deacetylase activity and phosphatidylinositol 3-kinase signaling. Clin Cancer Res. 2012 Aug 1;18(15):4104-13.
CAS Number
– 1339928-25-4
Molecular Weight
– C23H24N8O4S
Compound Purity
– 0.9966
SMILES
– COc1ccc(cn1)-c1nc(N2CCOCC2)c2sc(CN(C)c3ncc(cn3)C(=O)NO)cc2n1
Target
– Others
Pathway
– Apoptosis|||PI3K/Akt/mTOR signaling|||Chromatin/Epigenetic|||DNA Damage/DNA Repair
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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