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Emapalumab

SKU T76742-1 mg Category Brand:

Price range: 381 CAD through 3,984 CAD

Products Details

Product Description

– Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface receptors and activating inflammatory signaling. Emapalumab has a high binding force (Kd=1.4 pM) to free IFN-γ and to IFN-γ bound to its receptor. Emapalumab can be used in the study of hemophagocytic lymphohistiocytosis (HLH).

Web ID

– T76742

Storage Temperature

– -20℃

Shipping

– Blue Ice

References

– Vallurupalli M, et, al. Emapalumab for the treatment of relapsed/refractory hemophagocytic lymphohistiocytosis. Blood. 2019 Nov 21;134(21):1783-1786.

CAS Number

– 1709815-23-5

Molecular Weight

Compound Purity

– 97.56% (SEC-HPLC)

Pathway

– Immunology/Inflammation|||Neuroscience

Product type

– Inhibitory Antibodies

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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