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DK419

SKU T15137-1 mg Category Small Compound Brand: TargetMol

Price range: 126 CAD through 1,373 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM. DK419 decreases protein lelvels of Axin2, β-catenin, c-Myc, Cyclin D1 and Survivin.It also induces production of pAMPK.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T15137

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H8ClF6N3O

References

– Wang J, et al. Identification of DK419, a potent inhibitor of Wnt/β-catenin signaling and colorectal cancer growth. Bioorg Med Chem. 2018 Nov 1;26(20):5435-5442.

CAS Number

– 2102672-22-8

Molecular Weight

– C16H8ClF6N3O

Compound Purity

– 0.9815

SMILES

– FC(F)(F)c1nc2cc(Cl)cc(C(=O)Nc3ccc(cc3)C(F)(F)F)c2[nH]1

Target

– Others

Pathway

– Cytoskeletal Signaling|||Chromatin/Epigenetic|||PI3K/Akt/mTOR signaling|||Stem Cells

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.