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Desloratadine

SKU T2520-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 54 CAD through 94 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)100 mg 50 mg

Clear

Products Details

Product Description

– Desloratadine (Sch34117) is a long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic effects on H1-receptors in bronchial smooth muscle, capillaries and gastrointestinal smooth muscle, including vasodilation, bronchoconstriction, increased vascular permeability, pain, itching and spasmodic contractions of gastrointestinal smooth muscle. Desloratadine is used to provide symptomatic relieve of allergic symptoms.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2520

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H19ClN2

Citations

– 1. Dong L, Shen S, Chen W, et al. Discovery of Novel Inhibitors Targeting Human O-GlcNAcase: Docking-Based Virtual Screening, Biological Evaluation, Structural Modification, and Molecular Dynamics Simulation. Journal of chemical information and modeling. 2019, 59(10): 4374-4382. 2. Wang D, Guo Q, Wu Z, et al.Molecular mechanism of antihistamines recognition and regulation of the histamine H1 receptor.Nature Communications.2024, 15(1): 84. 3. Molecular mechanism of antihistamines recognition and regulation of the histamine H1 receptor

References

– 1. Cardelús I, et al. Eur J Pharmacol. 1999 Jun 18;374(2):249-54.

CAS Number

– 100643-71-8

Molecular Weight

– C19H19ClN2

Compound Purity

– 0.9979

SMILES

– ClC1=CC2=C(C=C1)C(=C1CCNCC1)C1=C(CC2)C=CC=N1

Pathway

– Immunology/Inflammation|||GPCR/G Protein|||Metabolism|||Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.