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RA-9

SKU T8464-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 46 CAD through 387 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 50 mg

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Products Details

Product Description

– RA-9 is a potent and selective proteasome-associated inhibitor of deubiquitinating enzymes (DUBs) with a favorable toxicity profile and anticancer activity, particularly effective in inducing apoptosis in ovarian cancer cell lines.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T8464

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H15N3O5

References

– Coughlin K , Anchoori R , Iizuka Y , et al. Small-molecule RA-9 inhibits proteasome-associated DUBs and ovarian cancer in vitro and in vivo via exacerbating unfolded protein responses.[J]. Clinical Cancer Research An Official Journal of the American Association for Cancer Research, 2014, 20(12):3174-86.

CAS Number

– 919091-63-7

Molecular Weight

– C19H15N3O5

Compound Purity

– 0.9815

SMILES

– [O-][N+](=O)c1ccc(C=C2/CNCC(=C/c3ccc(cc3)[N+]([O-])=O)C2=O)cc1

Pathway

– Ubiquitination|||Apoptosis|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.