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CAY10602

SKU T4062-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 75 CAD through 520 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– CAY10602 is a SIRT1 activator derived from high throughput screening for compounds that enhance SIRT1-mediated deacetylation of a SIRT1-specific substrate. Functional assays indicate that CAY10602 dose-dependently suppresses NF-κB-dependent induction of TNF-α by lipopolysaccharide in THP-1 cells, achieving approximately 75% inhibition at 60 μM without cytotoxicity.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T4062

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H15FN4O2S

Citations

– 1. Li M, Xu Q, Fan Q, et al.Small molecule SIRT1 activators counteract oxidative stress-induced inflammasome activation and nucleolar stress in retinal degeneration.International Immunopharmacology.2024, 142: 113167.

References

– Höppner S, et al. Fragmentation studies of SIRT1-activating drugs and their detection in human plasma for doping control purposes. Rapid Commun Mass Spectrom. 2013 Jan 15;27(1):35-50.

CAS Number

– 374922-43-7

Molecular Weight

– C22H15FN4O2S

Compound Purity

– 0.9892

SMILES

– Nc1c(c2nc3ccccc3nc2n1-c1ccc(F)cc1)S(=O)(=O)c1ccccc1

Pathway

– DNA Damage/DNA Repair|||Chromatin/Epigenetic

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.