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Bobcat339

SKU T5198-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 75 CAD through 621 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T5198

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H12ClN3O

Citations

– 1. Shi Q, Liu R, Chen L. Ferroptosis inhibitor ferrostatin-1 alleviates homocysteine-induced ovarian granulosa cell injury by regulating TET activity and DNA methylation. Molecular Medicine Reports. 2022, 25(4): 1-9 2. Xu X, Yuan X, Ni J, et al. MAGI2‐AS3 inhibits breast cancer by downregulating DNA methylation of MAGI2. Journal of Cellular Physiology. 2021, 236(2): 1116-1130 3. Shi Q, Liu R, Chen L. Ferroptosis inhibitor ferrostatin‑1 alleviates homocysteine‑induced ovarian granulosa cell injury by regulating TET activity and DNA methylation. Molecular Medicine Reports. 2022, 25(4): 1-9. 4. Li F, Dai P, Shi H, et al.LKB1 inactivation promotes epigenetic remodeling-induced lineage plasticity and antiandrogen resistance in prostate cancer.Cell Research.2025: 1-13.

References

– Chua GNL, et al. Cytosine-Based TET Enzyme Inhibitors. ACS Med Chem Lett. 2019 Jan 31;10(2):180-185.

CAS Number

– 2280037-51-4

Molecular Weight

– C16H12ClN3O

Compound Purity

– 0.9876

SMILES

– Nc1nc(=O)n(cc1Cl)-c1cccc(c1)-c1ccccc1

Pathway

– Chromatin/Epigenetic

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.