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Betahistine EP Impurity C

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Product Description

– Betahistine EP Impurity C (NSC19005) is an impurity of Betahistine[1]. Betahistine is a potent, orally active and well-tolerated histamine H1 receptor agonist and H3 receptor antagonist used for the study of rheumatoid arthritis (RA)[2][3].

Web ID

– HY-107495

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C15H19N3

References

Р[1]Murilo B. M. de Mello, et al. Characterization and in silico Mutagenic Assessment of a New Betahistine Degradation Impurity. J. Braz. Chem. Soc. vol.30 no.7 Ṣo Paulo July 2019 Epub July 04, 2019|[2]Poyurovsky M, et al. The effect of betahistine, a histamine H1 receptor agonist/H3 antagonist, on olanzapine-induced weight gain in first-episode schizophrenia patients. Int Clin Psychopharmacol. 2005 Mar;20(2):101-3.|[3]Betahistine EP Impurity C (NSC19005) is an impurity of Betahistine<sup>[1]</sup>. Betahistine is a potent, orally active and well-tolerated histamine H1 receptor agonist and H3 receptor antagonist used for the study of rheumatoid arthritis (RA)<sup>[2]</sup>.

CAS Number

– 5452-87-9

Molecular Weight

– 241.33

SMILES

– CN(CCC1=CC=CC=N1)CCC2=CC=CC=N2

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Histamine Receptor

Isoform

– H1 Receptor;H3 Receptor

Pathway

– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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