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AVN-944

SKU T1979-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 86 CAD through 1,101 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T1979

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H27N5O5

Citations

– 1. Zheng M, Li J, Guo H, et al.IMPDH inhibitors upregulate PD-L1 in cancer cells without impairing immune checkpoint inhibitor efficacy.Acta Pharmacologica Sinica.2024: 1-10.

References

– Zimmermann AG, et al. Prog Nucleic Acid Res Mol Biol. 1998;61:181-209.

CAS Number

– 297730-17-7

Molecular Weight

– C25H27N5O5

Compound Purity

– ≥95%

SMILES

– CC[C@H](CC#N)OC(=O)N[C@@H](C)c1cccc(NC(=O)Nc2ccc(-c3cnco3)c(OC)c2)c1

Pathway

– Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.