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Apinocaltamide

SKU T14120-2 mg Category Small Compound Brand: TargetMol

Price range: 142 CAD through 285 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 5 mg

Clear

Products Details

Product Description

– Apinocaltamide (ACT-709478) is an orally available and selective T-type calcium channel blocker that penetrates the blood-brain barrier (BBB) with IC50=6.4-18nM for Cav3.1, Cav3.2, and Cav3.3, and is commonly used in epilepsy research.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T14120

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H18F3N5O

References

– Bezençon O, et al. Discovery of a Potent, Selective T-type Calcium Channel Blocker as a Drug Candidate for the Treatment of Generalized Epilepsies. J Med Chem. 2017 Dec 14;60(23):9769-9789.

CAS Number

– 1838651-58-3

Molecular Weight

– C22H18F3N5O

Compound Purity

– 0.998

SMILES

– N#CC1=CN=C(C=C1)CN2N=C(C=C2)NC(=O)CC3=CC=C(C=C3)C4(CC4)C(F)(F)F

Target

– Others

Pathway

– Metabolism|||Membrane transporter/Ion channel

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.