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AAPK-25

SKU T10215-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 139 CAD through 2,016 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– AAPK-25 is a potent and selective Aurora/PLK dual inhibitor with anti-tumor activity, causing mitotic delay and arresting cells in prometaphase, followed by increased apoptosis. It targets Aurora-A/-B/-C with Kd values ranging from 23-289 nM.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T10215

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H13Cl2N3O2S

Citations

– 1. Liang L, Shen Z, Zhang K, et al.DLGAP5 upregulates E2F1 to promote prostate adenocarcinoma neuroendocrine differentiation.Life Sciences.2025: 123442.

References

– Qi B, et al. Discovery of inhibitors of Aurora/PLK targets as anti-cancer agents. J Med Chem. 2019 Aug 5.

CAS Number

– 2247919-28-2

Molecular Weight

– C21H13Cl2N3O2S

Compound Purity

– 0.9705

SMILES

– Clc1ccc(cc1Cl)C(=O)Nc1ccc2cc(ccc2c1)C(=O)Nc1nccs1

Target

– Others

Pathway

– Apoptosis|||Chromatin/Epigenetic|||Cell Cycle/Checkpoint

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.