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A 438079 hydrochloride

SKU T2673-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 66 CAD through 875 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– A 438079 hydrochloride (A-438079 HCl) is a potent and selective P2X7 receptor antagonist with pIC50 of 6.9.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2673

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C13H10Cl3N5

Citations

– 1. Wang J, Han Y, Wang M, et al. The inhibitory effect of Yam polysaccharides on acrylamide‐induced programmed cell death in RAW 264.7 cells. Food Science & Nutrition. 2022 2. Su Q, Tian Y, Liu Z, et al. Purinergic P2X7 receptor blockade mitigates alcohol-induced steatohepatitis and intestinal injury by regulating MEK1/2-ERK1/2 signaling and egr-1 activity. International Immunopharmacology. 2019 Jan;66:52-61 3. Zhang A, Jin D, Han Y, et al.The effects of Yam polysaccharides on acrylamide-induced RAW264. 7 cell polarization.Journal of Food Bioactives.2023, 23.

References

– McGaraughty S, et al. Neuroscience. 2007, 146(4), 1817-1828.

CAS Number

– 899431-18-6

Molecular Weight

– C13H10Cl3N5

Compound Purity

– 0.9989

SMILES

– Cl.Clc1cccc(-c2nnnn2Cc2cccnc2)c1Cl

Pathway

– Membrane transporter/Ion channel|||Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.