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3-Phenyltoxoflavin
$99 – $1,980
Products Details
Product Description
– 3-Phenyltoxoflavin, a derivative of Toxoflavin, is an Hsp90 inhibitor, with a Kd of 585 nM for the interaction of Hsp90-TPR2A. 3-Phenyltoxoflavin has anti-cancer activity[1][2].
Web ID
– HY-125759
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C13H11N5O2
References
– [1]Yi F, et, al. A novel class of small molecule inhibitors of Hsp90. ACS Chem Biol. 2008 Oct 17;3(10):645-54.|[2]Koh S, et, al. A novel light-dependent selection marker system in plants. Plant Biotechnol J. 2011 Apr;9(3):348-58.
CAS Number
– 32502-63-9
Molecular Weight
– 269.26
Compound Purity
– 99.86
SMILES
– O=C(C1=NC(C2=CC=CC=C2)=NN(C)C1=N3)N(C)C3=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 7.14 mg/mL (ultrasonic)
Target
– HSP
Isoform
– HSP90
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
