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(2R/S)-6-PNG

$290$2,370

Products Details

Product Description

– (2R/S)-6-PNG (6-Prenylnaringenin) is a potent and reversible Cav3.2 T-type Ca2+ channels (T-channels) blocker. (2R/S)-6-PNG can penetrate the blood-brain barrier (BBB). (2R/S)-6-PNG suppresses neuropathic and visceral pain in mice[1].

Web ID

– HY-115681

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C20H20O5

References

– [1]Fumiko Sekiguchi, et al. Blockade of T-type calcium channels by 6-prenylnaringenin, a hop component, alleviates neuropathic and visceral pain in mice. Neuropharmacology

CAS Number

– 68682-01-9

Molecular Weight

– 340.37

Compound Purity

– 99.88

SMILES

– O=C1CC(C2=CC=C(O)C=C2)OC3=CC(O)=C(C/C=C(C)C)C(O)=C13

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– DMSO : 125 mg/mL (ultrasonic)

Target

– Calcium Channel

Isoform

– T-type calcium channel

Pathway

– Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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