1,5-Isoquinolinediol

SKU T7042-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 46 CAD through 237 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– 1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM). The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1, 5-Isoquinolinediol has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. This compound can be used with cells in culture and in animals.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T7042

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C9H7NO2

References

– Davar D, et al. Role of PARP inhibitors in cancer biology and therapy.[J]. Current Medicinal Chemistry, 2012, 19(23).

CAS Number

– 5154-02-9

Molecular Weight

– C9H7NO2

Compound Purity

– 0.9943

SMILES

– Oc1cccc2c(O)nccc12

Pathway

– DNA Damage/DNA Repair|||Chromatin/Epigenetic

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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For Research Use Only. All Immunomart products are sold strictly for laboratory research use only (RUO). Not for human or veterinary consumption, therapeutic, or diagnostic use.