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10058-F4

SKU T3048-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 69 CAD through 955 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– 10058-F4 (c-Myc Inhibitor) is a cell-permeable thiazolidinone that specifically inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target gene expression; induces cell-cycle arrest and apoptosis.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T3048

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C12H11NOS2

Citations

– 1. Wang K, Du G, Qin X, et al. Compound Kushen Injection intervenes metabolic reprogramming and epithelial-mesenchymal transition of HCC via regulating β-catenin/c-Myc signaling. Phytomedicine. 2021: 153781. 2. Sequera C, Grattarola M, Holczbauer A, et al.MYC and MET cooperatively drive hepatocellular carcinoma with distinct molecular traits and vulnerabilities.Cell death & disease.2022, 13(11): 1-15. 3. Bi X, Zhang M, Zhou J, et al.Phosphorylated Hsp27 promotes adriamycin resistance in breast cancer cells through regulating dual phosphorylation of c-Myc.Cellular Signalling.2023: 110913. 4. He Q, Zhang Y, Li W, et al.Inhibition of PRMT5 moderately suppresses prostate cancer growth in vivo but enhances its response to immunotherapy.Cancer Letters.2024: 217214.

References

– Huang MJ, et al. Exp Hematol, 2006, 34(11), 1480-1489.

CAS Number

– 403811-55-2

Molecular Weight

– C12H11NOS2

Compound Purity

– 0.9982

SMILES

– CCC1=CC=C(C=C2/SC(=S)NC2=O)C=C1

Pathway

– Autophagy|||Cell Cycle/Checkpoint

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.