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Atorvastatin
Price range: 53 CAD through 446 CAD
Products Details
Product Description
– Atorvastatin, an orally active HMG-CoA reductase inhibitor, effectively lowers blood lipids by activating liver cytochrome p450 to accelerate metabolism. Atorvastatin inhibits the proliferation and invasion of human SV-SMC cells with IC50 values of 0.39 μM and 2.39 μM, respectively. [Atorvastatin] combined with clopidogrel may lead to increased thrombotic events in patients.
Web ID
– T20765
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C33H35FN2O5
Citations
– 1. Yang D, Fan Y, Xiong M, et al.Loss of renal tubular G9a benefits acute kidney injury by lowering focal lipid accumulation via CES1.EMBO reports.2023: e56128.
2. Zhang W, Chen L, Liu J, et al.Inhibition of autophagy-related protein 7 enhances anti-tumor immune response and improves efficacy of immune checkpoint blockade in microsatellite instability colorectal cancer.Journal of Experimental & Clinical Cancer Research.2024, 43(1): 1-19.
3. In vivo vulnerabilities to GPX4 and HDAC inhibitors in drug-persistent versus drug-resistant BRAFV600E lung adenocarcinoma
References
– Song XJ, et al. Atorvastatin inhibits myocardial cell apoptosis in a rat model with post-myocardial infarction heart failure by downregulating ER stress response. Int J Med Sci. 2011;8(7):564-72.
CAS Number
– 134523-00-5
Molecular Weight
– C33H35FN2O5
Compound Purity
– 0.9937
SMILES
– C(NC1=CC=CC=C1)(=O)C=2C(=C(N(CC[C@H](C[C@H](CC(O)=O)O)O)C2C(C)C)C3=CC=C(F)C=C3)C4=CC=CC=C4
Target
– Others
Pathway
– Autophagy|||Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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