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DMOG

SKU T1939-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 51 CAD through 429 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 50 mg 500 mg

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Products Details

Product Description

– DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T1939

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C6H9NO5

Citations

– 1. Zheng B X, Long W, Zheng W, et al.Mitochondria-Selective Dicationic Small-Molecule Ligand Targeting G-Quadruplex Structures for Human Colorectal Cancer Therapy.Journal of Medicinal Chemistry.2024 2. Ma X, Li M, Wang X, et al.Dihydromyricetin ameliorates experimental ulcerative colitis by inhibiting neutrophil extracellular traps formation via the HIF-1α/VEGFA signaling pathway.International Immunopharmacology.2024, 138: 112572.

References

– Singh A, et al. Hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitors induce autophagy and have a protective effect in an in-vitro ischaemia model. Sci Rep. 2020 Jan 31;10(1):1597.

CAS Number

– 89464-63-1

Molecular Weight

– C6H9NO5

Compound Purity

– 0.9826

SMILES

– COC(=O)CNC(=O)C(=O)OC

Target

– Others

Pathway

– Autophagy|||Metabolism|||Chromatin/Epigenetic|||Angiogenesis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.