H3B-968
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H3B-968

SKU T78938-5 mg Category Brand:

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Product Description

– H3B-968 is a potent inhibitor of Werner syndrome protein (WRN) with an IC50 of approximately 10 nM, targeting its helicase, ATPase, and exonuclease activities. While WRN is known for its synthetic lethal activity in cancer studies, H3B-968 specifically inhibits WRN’s helicase function through competitive ATP antagonism [1].

Web ID

– T78938

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H18F6N4O4S

CAS Number

– 2912294-90-5

Molecular Weight

– C22H18F6N4O4S

SMILES

– S(NCC(NC1=CC=C(CC)C=C1)=O)(=O)(=O)C=2N=C(C=C(C(F)(F)F)N2)C3=CC=C(OC(F)(F)F)C=C3

Pathway

– DNA Damage/DNA Repair|||Cell Cycle/Checkpoint

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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