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GDC-0575

SKU T7300-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 51 USD through 890 USD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– GDC-0575 (ARRY-575) is a highly-selective oral small-molecule Chk1 inhibitor(IC50 of 1.2 nM).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T7300

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H20BrN5O

References

– Oo Z Y , Stevenson A J , Proctor M A , et al. Endogenous replication stress marks melanomas sensitive to CHK1 inhibitors in vivo[J]. Clinical Cancer Research, 2018:clincanres.2701.2017.

CAS Number

– 1196541-47-5

Molecular Weight

– C16H20BrN5O

Compound Purity

– 0.98

SMILES

– N[C@@H]1CCCN(C1)c1c(Br)cnc2[nH]cc(NC(=O)C3CC3)c12

Pathway

– Cell Cycle/Checkpoint

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.