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SNS-032

SKU T6049-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 69 CAD through 894 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– SNS-032 (BMS-387032) is a selective inhibitor of CDK2 (IC50: 48 nM), exhibiting 10- and 20-fold selectivity over CDK1 and CDK4, respectively. It is also sensitive to CDK7 (IC50: 62 nM) and CDK9 (IC50: 4 nM), with no effect on CDK6.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T6049

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H24N4O2S2

Citations

– 1. Zhang G M, Huang S S, Ye L X, et al. Reciprocal positive regulation between BRD4 and YAP in GNAQ-mutant uveal melanoma cells confers sensitivity to BET inhibitors. Pharmacological Research. 2022: 106464. 2. Guo S, Lei X, Chang Y, et al.SARS-CoV-2 hijacks cellular kinase CDK2 to promote viral RNA synthesis.Signal Transduction and Targeted Therapy.2022, 7(1): 1-12.

References

– Chen R, et al. Blood, 2009, 113(19): 4637-45.

CAS Number

– 345627-80-7

Molecular Weight

– C17H24N4O2S2

Compound Purity

– 0.9944

SMILES

– C(SC=1SC(NC(=O)C2CCNCC2)=NC1)C=3OC(C(C)(C)C)=CN3

Pathway

– PI3K/Akt/mTOR signaling|||Cell Cycle/Checkpoint|||Stem Cells|||Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.