PD-1/PD-L1-IN-NP19

SKU T36900-5 mg Category Brand:

Price range: 602 CAD through 3,776 CAD

Products Details

Product Description

– PD-1/PD-L1-IN-NP19, a PD-1/PD-L1 inhibitor, exhibits an IC50 of 12.5 nM against the human PD-1/PD-L1 interaction, potentially activating the tumor immune microenvironment and contributing to its antitumor effects[1].

Web ID

– T36900

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C33H31ClN2O4

References

– Cheng B, et, al. Discovery of Novel Resorcinol Dibenzyl Ethers Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction As Potential Anticancer Agents. J Med Chem. 2020 Jul 15.

CAS Number

– 2377916-66-8

Molecular Weight

– C33H31ClN2O4

SMILES

– Cc1c(COc2cc(OCc3cccc(c3)C#N)c(CNC(C)(C)C(O)=O)cc2Cl)cccc1-c1ccccc1

Pathway

– Apoptosis|||Cell Cycle/Checkpoint|||Immunology/Inflammation

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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