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Nocodazole

SKU T2802-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 50 CAD through 1,149 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– Nocodazole (Oncodazole) is a reversible inhibitor of microtubule polymerization and an inhibitor of Bcr-Abl. Nocodazole has antitumor activity, blocks the cell cycle and induces apoptosis.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2802

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C14H11N3O3S

Citations

– 1. Bai Y, Wang W, Li S, et al. C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex. Molecular Cell. 2019 2. Moreira G G, Cantrelle F X, Quezada A, et al. Dynamic interactions and Ca2+-binding modulate the holdase-type chaperone activity of S100B preventing tau aggregation and seeding. Nature Communications. 2021, 12(1): 1-16 3. Reyes G X, Kolodziejczak A, Devakumar L J P S, et al. Ligation of newly replicated DNA controls the timing of DNA mismatch repair. Current Biology.. 2021 Mar 22;31(6):1268-1276.e6. doi: 10.1016/j.cub.2020.12.018. Epub 2021 Jan 7. 4. Li X, Tang H, Huang X, et al. Rigidity‐Dependent Placental Cells Uptake of Silk‐Based Microcapsules. Macromolecular bioscience. 2019: 1900105. 5. Cui L, Xu Q, Zhang P, et al.Biochemical reprogramming of active-targeting and redox responsive nanoparticles for enhancing selective internalization.Materials Letters.2023: 134379. 6. Wang J, Chen Y, Li S, et al.PP2A inhibition causes synthetic lethality in BRCA2-mutated prostate cancer models via reactivating spindle assembly checkpoint.The Journal of Clinical Investigation.2023

References

– Signoretto E, et al. Nocodazole Induced Suicidal Death of Human Erythrocytes. Cell Physiol Biochem. 2016;38(1):379-92.

CAS Number

– 31430-18-9

Molecular Weight

– C14H11N3O3S

Compound Purity

– 0.9865

SMILES

– COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c1cccs1

Pathway

– Autophagy|||Angiogenesis|||DNA Damage/DNA Repair|||Cytoskeletal Signaling|||Apoptosis|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.