Difamilast
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Difamilast

SKU T27172-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 101 CAD through 2,048 CAD

Products Details

Product Description

– Difamilast is a selective inhibitor of phosphodiesterase-4 (PDE4) with particularly efficient inhibition of subtype B (IC50=11.2 nM).

Web ID

– T27172

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H24F2N2O5

Citations

– 1. Mikheil D, Larsen M A, Hsiao K, et al.A bioluminescent and homogeneous assay for monitoring GPCR-mediated cAMP modulation and PDE activity.Scientific Reports.2024, 14(1): 4440.

References

– Ahluwalia J, et, al. Phosphodiesterase 4 Inhibitor Therapies for Atopic Dermatitis: Progress and Outlook. Drugs. 2017 Sep;77(13):1389-1397.

CAS Number

– 937782-05-3

Molecular Weight

– C23H24F2N2O5

Compound Purity

– 0.9904

SMILES

– CCOc1ccccc1C(=O)NCc1coc(n1)-c1ccc(OC(F)F)c(OC(C)C)c1

Pathway

– Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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