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Gandotinib

SKU T2638-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 75 CAD through 1,744 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM). The selectivity is higher 8- and 20-fold than JAK1 and JAK3.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2638

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H25ClFN7O

References

– Ma L, et al. 53rd ASH Annual Meeting and Exposition, 2011, Abstract 4087.

CAS Number

– 1229236-86-5

Molecular Weight

– C23H25ClFN7O

Compound Purity

– 0.9986

SMILES

– C(C=1C=2N(C(CC3=C(F)C=C(Cl)C=C3)=C(C)N2)N=C(NC=4C=C(C)NN4)C1)N5CCOCC5

Pathway

– Stem Cells|||Chromatin/Epigenetic|||Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.