AACOCF3
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AACOCF3

SKU T21681-1 mg Category Brand:

Price range: 112 CAD through 237 CAD

Products Details

Product Description

– AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeable trifluoromethyl ketone analog of arachidonic acid and a potent, selective slow binding inhibitor of the 85-kDa cytosolic phospholipase A2 (cPLA2). By blocking the production of arachidonate and 12-hydroxyeicosatetraenoic acid in calcium ionophore-challenged platelets, AACOCF3 hinders their synthesis. Additionally, AACOCF3 inhibits glucose-induced insulin secretion from isolated rat islets, making it promising for cardiovascular disease research.

Web ID

– T21681

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H31F3O

References

– Riendeau D, et al. Arachidonyl trifluoromethyl ketone, a potent inhibitor of 85-kDa phospholipase A2, blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets. J Biol Chem. 1994;269(22):15619-15624.

CAS Number

– 149301-79-1

Molecular Weight

– C21H31F3O

Compound Purity

– 0.99

SMILES

– C(CCCC(C(F)(F)F)=O)=CC/C=CC/C=CC/C=CCCCCC

Pathway

– Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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