Akt1 and Akt2-IN-1

SKU T14152-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 555 CAD through 3,184 CAD

Products Details

Product Description

– Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 (IC50=3.5 nM) and Akt2 (IC50=42 nM). It has potent and balanced activity.

Web ID

– T14152

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C33H29N7O

References

– Bilodeau MT, Allosteric inhibitors of Akt1 and Akt2: a naphthyridinone with efficacy in an A2780 tumor xenograft model. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3178-82.

CAS Number

– 893422-47-4

Molecular Weight

– C33H29N7O

SMILES

– O=c1[nH]ccc2nc(-c3ccc(CN4CCC(CC4)c4n[nH]c(n4)-c4ccccn4)cc3)c(cc12)-c1ccccc1

Pathway

– Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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