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JAK1-IN-4
Price range: 2,672 CAD through 4,480 CAD
Products Details
Product Description
– JAK1-IN-4 is a selective JAK1 inhibitor (IC50s: 85 nM, 12.8 μM and >30 μM for JAK1, JAK2, and JAK3, respectively). JAK1-IN-4 inhibits STAT3 phosphorylation in NCI-H 1975 cells (IC50, 227 nM).
Web ID
– T15606
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C26H32FN9O2
References
– Annika Birgitta Margareta ÅSTRAND, et al. Compounds and methods for inhibiting jak.
CAS Number
– 2091134-35-7
Molecular Weight
– C26H32FN9O2
SMILES
– N(C([C@@H](C)N1C[C@@H](C)N(C)CC1)=O)C2=C3C(C(=CN3)C4=NC(NC=5C(OC)=NN(C)C5)=NC=C4F)=CC=C2
Target
– Others
Pathway
– JAK/STAT signaling|||Angiogenesis|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors|||Stem Cells
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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