Glesatinib hydrochloride
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Glesatinib hydrochloride

SKU T15383-25 mg Category Brand:

Price range: 1,526 CAD through 3,184 CAD

Products Details

Product Description

– Glesatinib hydrochloride is an orally active and potent dual inhibitor of MET/SMO. Glesatinib hydrochloride is also a tyrosine kinase inhibitor. It antagonizes P-glycoprotein mediated multidrug resistance (MDR) in NSCLC.

Web ID

– T15383

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C31H28ClF2N5O3S2

References

– Morgillo F, et al. Dual MET and SMO Negative Modulators Overcome Resistance to EGFR Inhibitors in Human Nonsmall Cell Lung Cancer. J Med Chem. 2017 Sep 14;60(17):7447-7458.

CAS Number

– 1123838-51-6

Molecular Weight

– C31H28ClF2N5O3S2

SMILES

– Cl.COCCNCc1ccc(nc1)-c1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccc(F)cc4)cc3F)c2s1

Target

– Others

Pathway

– Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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