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NMS-859

SKU T12236-1 mg Category Small Compound Brand: TargetMol

Price range: 155 CAD through 2,848 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– NMS-859 is an effective and covalent inhibitor of valosin-containing protein (VCP)/p97 with IC50s of 0.37 μM and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T12236

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H12ClN3O3S

References

– Magnaghi P, et al. Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death. Nat Chem Biol. 2013 Sep;9(9):548-56.

CAS Number

– 1449236-96-7

Molecular Weight

– C15H12ClN3O3S

Compound Purity

– 0.9736

SMILES

– ClCC(=O)OC1=CC=CC(NC2=NS(=O)(=O)C3=C2C=CC=C3)=C1

Target

– c-Met/HGFR|||HDAC|||Apoptosis

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.