MSC1094308
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MSC1094308

SKU T12114-2 mg Category Brand:

493 CAD

Only 1000 item(s) left in stock.

Products Details

Product Description

– MSC1094308 is a reversible, non-ATP-competitive alterative inhibitor targeting type II AAA ATPase (VCP/p97) and type I AAA ATPase (VPS4B), which affects the intracellular protein degradation process by binding to a specific hotspot region of p97 and inhibiting D2 ATPase activity.

Web ID

– T12114

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H29F3N2

References

– Pöhler R, et al. A Non-Competitive Inhibitor of VCP/p97 and VPS4 Reveals Conserved Allosteric Circuits in Type I and II AAA ATPases. Angew Chem Int Ed Engl. 2018 Feb 5;57(6):1576-1580.

CAS Number

– 2219320-08-6

Molecular Weight

– C29H29F3N2

SMILES

– FC1=CC=C(C=C1)C(C2=CC=C(F)C=C2)CCCNCC3CC=4C=5C=C(F)C=CC5NC4CC3

Target

– Apoptosis|||Guanylate cyclase

Pathway

– Ubiquitination

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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