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Products Details
Product Description
– MSC1094308 is a reversible, non-ATP-competitive alterative inhibitor targeting type II AAA ATPase (VCP/p97) and type I AAA ATPase (VPS4B), which affects the intracellular protein degradation process by binding to a specific hotspot region of p97 and inhibiting D2 ATPase activity.
Web ID
– T12114
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C29H29F3N2
References
– Pöhler R, et al. A Non-Competitive Inhibitor of VCP/p97 and VPS4 Reveals Conserved Allosteric Circuits in Type I and II AAA ATPases. Angew Chem Int Ed Engl. 2018 Feb 5;57(6):1576-1580.
CAS Number
– 2219320-08-6
Molecular Weight
– C29H29F3N2
SMILES
– FC1=CC=C(C=C1)C(C2=CC=C(F)C=C2)CCCNCC3CC=4C=5C=C(F)C=CC5NC4CC3
Target
– Apoptosis|||Guanylate cyclase
Pathway
– Ubiquitination
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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