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eIF4A3-IN-1

SKU T11170-1 mg Category Small Compound Brand: TargetMol

Price range: 232 CAD through 1,872 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– eIF4A3-IN-1 is a selective and potent inhibitor of eukaryotic initiation factor 4A3 (eIF4A3) with an IC50 value of 0.26 μM. eIF4A3-IN-1 inhibits cytosolic nonsense-mediated RNA decay at high concentrations.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T11170

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H23BrClN5O2

References

– Ito M, et al. Discovery of Novel 1,4-Diacylpiperazines as Selective and Cell-Active eIF4A3 Inhibitors. J Med Chem. 2017 Apr 27;60(8):3335-3351.

CAS Number

– 2095486-67-0

Molecular Weight

– C29H23BrClN5O2

Compound Purity

– 0.9949

SMILES

– C(=O)(N1[C@H](CN(C(=O)C2=C(C)N(N=C2)C3=CC(C#N)=CC=C3)CC1)C4=CC=C(Cl)C=C4)C5=CC=C(Br)C=C5

Target

– Adrenergic Receptor|||AChR|||Norepinephrine|||5-HT Receptor|||Histamine Receptor|||Cytochromes P450|||Dopamine Receptor

Pathway

– Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.