Download Files:

YAP-TEAD-IN-1 TFA

SKU TP2160L-1 mg Category Peptide Brand: TargetMol

Price range: 240 CAD through 914 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 10 mg 5 mg

Clear

Products Details

Product Description

– YAP-TEAD-IN-1 TFA, a competitive inhibitor of the YAP–TEAD interaction (IC50: 25 nM), exhibits higher binding affinity to TEAD1 (Kd: 15 nM) compared to YAP (50-171) (Kd: 40 nM).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– TP2160L

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C93H144ClN23O21S2.xC2HF3O2

Citations

– 1. Effects of YAP Inhibitors and Activators on the Growth of Leukemia Cells[J]. Anticancer Research, 2025, 45(3): 977-987.

References

– Zhang Z, et al. Structure-Based Design and Synthesis of Potent Cyclic Peptides Inhibiting the YAP-TEAD Protein-Protein Interaction.ACS Med Chem Lett. 2014 Jul 14;5(9):993-8.

CAS Number

– 1659305-79-9

SMILES

– C(C(O)=O)(F)(F)F.C(=O)([C@H]1N(C([C@@H](NC(=O)[C@H]2NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@]4(N(C(=O)[C@H](CCCC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC([C@@H](NC(=O)[C@H]5N(C([C@@H](NC(C)=O)C(C)C)=O)CCC5)CC6=CC(Cl)=CC=C6)=O)CCSSC2)CCC4)[H])CCCCN)=O)CCC1)N7[C@H](C(N[C@@H](CCC(O)=O)C(N)=O)=O)CCC7

Pathway

– Others

Product type

– Peptide

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.