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XY221
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– XY221 (Compound 16o) selectively inhibits BRD4 BD2 with an IC50 of 5.8 nM. It demonstrates high selectivity for pan-BD2 and BRD4 BD2 domains, being 667 times more selective than for BRD4 BD1, and 9-32 times more selective than for BRD2/3/T BD2. XY221 can induce apoptosis in MV4-11 cells and exhibits anti-cancer activity.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T204924
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C32H34FN3O5
Molecular Weight
– C32H34FN3O5
SMILES
– CCC1=NC(=C(N1)COC)C2=CC3=C(O2)C(=CN(C3=O)C)C4=C(C=CC(=C4)C(C)(C)O)OC5=C(C=C(C=C5C)F)C
Target
– Others
Pathway
– Chromatin/Epigenetic|||Apoptosis|||Cell Cycle/Checkpoint|||Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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