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XL177A

SKU T9122-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 155 CAD through 1,728 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– XL177A is a selective irreversible USP7 inhibitor(IC50: 0.34 nM). XL177A elicits cancer cell killing through a p53-dependent mechanism.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T9122

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C48H57ClN8O5

References

– Nathan J Schauer, et al. Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism. Sci Rep.2020 Mar 24;10(1):5324.

CAS Number

– 2417089-74-6

Molecular Weight

– C48H57ClN8O5

Compound Purity

– 0.9875

SMILES

– CN1CCN(CCC(=O)Nc2ccc3c(c2)ncn(CC2(O)CCN(CC2)C(=O)[C@@H](CCCNC(=O)c2ccc4c(Cl)c5CCCCc5nc4c2)Cc2ccccc2)c3=O)CC1

Pathway

– Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Ubiquitination

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.