Troglitazone

SKU T3170-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 56 CAD through 1,968 CAD

Products Details

Product Description

– Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.

Web ID

– T3170

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H27NO5S

Citations

– 1. Kazberuk A, Chalecka M, Palka J, et al. Nonsteroidal Anti-Inflammatory Drugs as PPARγ Agonists Can Induce PRODH/POX-Dependent Apoptosis in Breast Cancer Cells: New Alternative Pathway in NSAID-Induced Apoptosis. International Journal of Molecular Sciences. 2022, 23(3): 1510. 2. Han L, Song B, Zhang P, et al.PC3T: a signature-driven predictor of chemical compounds for cellular transition.Communications Biology.2023, 6(1): 989. 3. Huang Q, Ru Y, Luo Y, et al.Identification of a targeted ACSL4 inhibitor to treat ferroptosis-related diseases.Science Advances.2024, 10(13): eadk1200.

References

– Fujita M, et al. In vitro and in vivo cytotoxicity of troglitazone in pancreatic cancer. J Exp Clin Cancer Res. 2017 Jul 3;36(1):91.

CAS Number

– 97322-87-7

Molecular Weight

– C24H27NO5S

Compound Purity

– 0.9936

SMILES

– Cc1c(C)c2OC(C)(COc3ccc(CC4SC(=O)NC4=O)cc3)CCc2c(C)c1O

Target

– Lipoxygenase|||NF-κB|||Leukotriene Receptor

Pathway

– Metabolism|||Apoptosis|||DNA Damage/DNA Repair|||Autophagy

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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