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Trifluridine

SKU T1428-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 48 CAD through 357 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 50 mg 500 mg

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Products Details

Product Description

– Trifluridine (NSC-75520) is a fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate synthase, resulting in inhibition of DNA synthesis, inhibition of protein synthesis, and apoptosis. This agent also exhibits antiviral activity.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T1428

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C10H11F3N2O5

Citations

– 1. Dsouza L, Pant A, Offei S, et al.Antiviral activities of two nucleos (t) ide analogs against vaccinia, mpox, and cowpox viruses in primary human fibroblasts.Antiviral Research.2023: 105651. 2. Luo P Q, Zhang L X, Chen Z M, et al.Effects and mechanisms of trifluridine alone or in combination with cryptotanshinone in inhibiting malignant biological behavior of gastric cancer.Cell Cycle.2023: 1-15.

References

– Yamashita F, et al. Cancer Chemother Pharmacol,2015 Jun 18.

CAS Number

– 70-00-8

Molecular Weight

– C10H11F3N2O5

Compound Purity

– 0.9939

SMILES

– O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=C(C(F)(F)F)C(=O)N1

Target

– Others

Pathway

– Microbiology/Virology|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.