TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Recombinant (His)

SKU TMPK-01382-100 μg Category Recombinant-Protein Brand: TargetMol

Price range: 594 CAD through 2,384 CAD

Size

100 μg 500 μg

Clear

Products Details

Product Description

– Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa.Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– TMPK-01382

Storage Temperature

– -20℃

Shipping

– Blue Ice

References

– Vanamee, et al. TNFR2: A Novel Target for Cancer Immunotherapy[J]. Trends in Molecular Medicine, 2017:S1471491417301697.

Molecular Weight

Product type

– Recombinant-Protein

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.