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Tinengotinib

SKU T39718-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 98 CAD through 1,043 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– Tinengotinib is a multikinase inhibitor targeting a series of kinases involved in cancer cell proliferation, angiogenesis, and regulation of immune response, including Aurora kinase A/B, Janus kinase (JAK1/2), fibroblast growth factor receptor (FGFR1/2/3), vascular endothelial growth factor receptors (VEGFRs), and other tyrosine kinases. Tinengotinib has shown good tolerability and preliminary efficacy in clinical trials in a variety of advanced solid tumors.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T39718

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H19ClN6O

References

– Wu, Yongqian, et al. Multi-kinase inhibitor compound, and crystal form and use thereof. Patent WO2018108079A1.

CAS Number

– 2230490-29-4

Molecular Weight

– C20H19ClN6O

Compound Purity

– 0.9905

SMILES

– ClC=1C=CC=CC1C2=NC=3C(=NNC3C)NC=4C=C(N=CC24)N5CCOCC5

Pathway

– Chromatin/Epigenetic|||JAK/STAT signaling|||Cell Cycle/Checkpoint|||Angiogenesis|||Tyrosine Kinase/Adaptors|||Stem Cells

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.