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Ticolubant

SKU T28974-1 mg Category Small Compound Brand: TargetMol

Price range: 202 CAD through 2,928 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– Ticolubant is orally active leukotriene B4 antagonist with high affinity for the human neutrophil LTB4 receptor (Ki = 0.78 nM), blocks LTB4-induced Ca2+ migration with an IC50 of 6.6 ± 1.5 nM, and shows topical anti-inflammatory activity in a mouse model of skin inflammation.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T28974

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H19Cl2NO3S

References

– Gearing KL, et al. Complex chimeras to map ligand binding sites of GPCRs. Protein Eng. 2003;16(5):365-372.

CAS Number

– 154413-61-3

Molecular Weight

– C23H19Cl2NO3S

Compound Purity

– 0.9933

SMILES

– C(=C/C(O)=O)C1=C(OCCC2=CC=CC=C2)C=CC(CSC3=C(Cl)C=CC=C3Cl)=N1

Pathway

– Metabolism|||Membrane transporter/Ion channel|||Immunology/Inflammation

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.