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Thonzonium Bromide

SKU T2188-5 mg Category Small Compound Brand: TargetMol

Price range: 48 CAD through 1,061 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– Thonzonium bromide is a mono-cationic surfactant that is structurally similar to Farnesol as an antimicrobial agent. It inhibits proton transport in a dose-dependent manner (EC50=69 μM). It inhibits RANKL-induced osteoclast formation and bone resorption in vitro and prevents LPS-induced bone loss in vivo.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2188

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C32H55BrN4O

References

– Chan, C., Prudom, C., Raines, S., Charkhzarrin, S., Melman, S., & De Haro, L. et al. (2012). Inhibitors of V-ATPase Proton Transport Reveal Uncoupling Functions of Tether Linking Cytosolic and Membrane Domains of V 0 Subunit a (Vph1p). Journal Of Biological Chemistry, 287(13), 10236-10250. doi: 10.1074/jbc.m111.321133

CAS Number

– 553-08-2

Molecular Weight

– C32H55BrN4O

Compound Purity

– 0.9893

SMILES

– [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)CCN(Cc1ccc(OC)cc1)c1ncccn1

Pathway

– Autophagy|||Membrane transporter/Ion channel|||Microbiology/Virology

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.