Download Files:

Thapsigargin

SKU TQ0302-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 131 CAD through 912 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)

Clear

Products Details

Product Description

– Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer. Thapsigargin increases cytoplasmic calcium concentration by blocking the ability of cells to pump calcium into the sarcoplasmic and endoplasmic reticulum.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– TQ0302

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C34H50O12

Citations

– 1. Shang Z, Zhang S, Wang J, et al.TRIM25 predominately associates with anti-viral stress granules.Nature Communications.2024, 15(1): 4127. 2. Xu W, Wang Z, Liu T, et al.Eurycomanone inhibits osteosarcoma growth and metastasis by suppressing GRP78 expression.Journal of Ethnopharmacology.2024: 118709. 3. Wang L, Wu J, Sramek M, et al.Heterogeneous enhancer states orchestrate β cell responses to metabolic stress.Nature Communications.2024, 15(1): 9361. 4. Zhou J, Shi Y, Zhao L, et al.γ-Glutamylcysteine restores glucolipotoxicity-induced islet β-cell apoptosis and dysfunction via inhibiting endoplasmic reticulum stress.Toxicology and Applied Pharmacology.2025, 495: 117206.

References

– Wang H, et al. Effects of thapsigargin on the proliferation and survival of human rheumatoid arthritis synovial cells. ScientificWorldJournal. 2014 Feb 9;2014:605416.

CAS Number

– 67526-95-8

Molecular Weight

– C34H50O12

Compound Purity

– 0.993

SMILES

– CCCCCCCC(=O)O[C@@H]1[C@@H](OC(=O)C(C)=CC)C(C)=C2[C@@H]3OC(=O)[C@@](C)(O)[C@@]3(O)[C@H](C[C@](C)(OC(C)=O)[C@@H]12)OC(=O)CCC

Pathway

– Apoptosis|||Microbiology/Virology|||Membrane transporter/Ion channel|||Metabolism

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.