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Products Details
Product Description
– TGFBR1-IN-1 is an ALK5 inhibitor extracted from patent WO2018004290A1, Compound 33, has an IC50 of 10-100 nM[1].
Web ID
– HY-129171
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C23H17N5O2S
References
– [1]Novel pyrazole derivative as alk5 inhibitor and uses thereof. WO2018004290A1.
CAS Number
– 2170830-26-7
Molecular Weight
– 427.48
SMILES
– O=C(C1=NN(C2=NC(C)=CC=C2)C(C3=CC=C4N=CSC4=C3)=C1)NC5=CC=C(O)C=C5
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– TGF-β Receptor
Isoform
– ALK5
Pathway
– TGF-beta/Smad
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
