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TG6-129

SKU T28958-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 197 CAD through 4,512 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– TG6-129 is an antagonist of the EP2 receptor. TG6-129 suppresses PGE2-induced elevation of cAMP in cells expressing EP2 with an IC50 value of 1.6 µM. TG6-129 reduces the expression of COX-2, IL-1β, IL-6, IL-12, IL-23 and TNF-α induced by the EP2-selective agonist butaprost in P388D1 macrophages.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T28958

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H18FN5O3S3

References

– Ganesh T, Jiang J, Shashidharamurthy R, Dingledine R. Discovery and characterization of carbamothioylacrylamides as EP(2) selective antagonists. ACS Med Chem Lett. 2013 Jul 11;4(7):616-621. PubMed PMID: 23914286; PubMed Central PMCID: PMC3731160.

CAS Number

– 1164464-14-5

Molecular Weight

– C20H18FN5O3S3

Compound Purity

– 0.9839

SMILES

– CCC1=NN=C(NS(=O)(=O)C2=CC=C(NC(=S)NC(=O)C=CC3=CC=C(F)C=C3)C=C2)S1

Pathway

– GPCR/G Protein|||Immunology/Inflammation

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.