Download Files:
TG100-115
$106 – $515
Products Details
Product Description
– TG100-115 is a selective PI3Kγ/PI3Kδ inhibitor with IC50s of 83 and 235 nM, respectively.
Web ID
– HY-10111
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C18H14N6O2
References
– [1]Doukas J, et al. Phosphoinositide 3-kinase gamma/delta inhibition limits infarct size after myocardial ischemia/reperfusion injury. Proc Natl Acad Sci U S A. 2006 Dec 26;103(52):19866-71.
CAS Number
– 677297-51-7
Molecular Weight
– 346.34
Compound Purity
– 99.01
SMILES
– NC1=C(C(N=C2C3=CC(O)=CC=C3)=NC(N)=N1)N=C2C4=CC(O)=CC=C4
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease; Cancer
Solubility
– DMSO : 33.33 mg/mL (ultrasonic;warming;adjust pH to 2 with HCl;heat to 60°C)
Target
– PI3K
Isoform
– PI3Kγ;PI3Kδ
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
