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Tebufelone

SKU T68155-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 83 CAD through 2,176 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– Tebufelone is a potent in vitro inhibitor of CO, a novel non-steroidal anti-inflammatory drug (NSAID) belonging to the di-tert-butylphenol (DTBP) class that has shown potent anti-inflammatory, analgesic and anti-reticulitis properties in various animal models. Tebufelone potently inhibits the formation of prostaglandins (PGE2) and blocks the formation of lipoxygenase pathway products [leukotriene (LTB4)] in rat macrophages (IC50 = 20 microM) and human whole blood (IC50 = 22 microM) in vitro. = 20 microM) and human whole blood (IC50 = 22 microM) from the formation of lipoxygenase pathway products [leukotriene (LTB4)] in vitro.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T68155

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H28O2

References

– Powell JH, et al. Antipyretic activity of tebufelone (NE-11740) in man. Agents Actions Suppl. 1991 ; 32:45-49.

CAS Number

– 112018-00-5

Molecular Weight

– C20H28O2

Compound Purity

– 0.9952

SMILES

– OC1=C(C(C)(C)C)C=C(C(CCCC#C)=O)C=C1C(C)(C)C

Pathway

– Immunology/Inflammation|||GPCR/G Protein

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.