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TD139

SKU T5121-1 mg Category Small Compound Brand: TargetMol

Price range: 102 CAD through 2,064 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– TD139 is a small molecule inhibitor of inhaled galectin-3 (Gal-3) with potential anti-fibrotic activity, commonly used in the study of idiopathic pulmonary fibrosis.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T5121

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H30F2N6O8S

Citations

– 1. Liu Y, Zhao C, Meng J, et al. Galectin-3 regulates microglial activation and promotes inflammation through TLR4/MyD88/NF-kB in experimental autoimmune uveitis. Clinical Immunology. 2022: 108939. 2. Xiao H, Wang T, Gao B, et al.The effects of a galectin‐3 inhibitor on bladder pain syndrome in mice with cyclophosphamide‐induced cystitis.Neurourology and Urodynamics.2024 3. Chen Y, Zhang W, Cheng M, et al.Galectin-3-ITGB1 Signaling Mediates Interleukin 10 Production of Hepatic Conventional Natural Killer Cells in Chronic Hepatitis Virus B Transgenic Mice and Correlates with Hepatocellular Carcinoma Progression in Patients.Viruses.2024, 16(5): 737. 4. Shen Y, Zhang W, Chang H, et al.Galectin-3 modulates microglial activation and neuroinflammation in early brain injury after subarachnoid hemorrhage.Experimental Neurology.2024: 114777. 5. Liu J, Zhang X, Liu Y, et al.Intestinal lymphatic transport of Smilax china L. pectic polysaccharide via Peyer’s patches and its uptake and transport mechanisms in mononuclear phagocytes.Carbohydrate Polymers.2024: 122256.

References

– Mackinnon AC, et al. Regulation of transforming growth factor-β1-driven lung fibrosis by galectin-3. Am J Respir Crit Care Med. 2012 Mar 1;185(5):537-46.

CAS Number

– 1450824-22-2

Molecular Weight

– C28H30F2N6O8S

Compound Purity

– 0.9948

SMILES

– OC[C@H]1O[C@@H](S[C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cccc(F)c2)[C@H](O)[C@H]([C@H]1O)n1cc(nn1)-c1cccc(F)c1

Pathway

– Immunology/Inflammation

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.