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TCS-PIM-1-4a

SKU T4215-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 75 CAD through 542 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– TCS-PIM-1-4a (SMI-4a), a Pim inhibitor, blocks mTORC1 activity through activation of AMPK and kills a wide range of both myeloid and lymphoid cell lines (IC50=0.8-40 μM).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T4215

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C11H6F3NO2S

References

– Lin YW, et al. A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma. Blood. 2010 ;115(4):824-33.

CAS Number

– 327033-36-3

Molecular Weight

– C11H6F3NO2S

Compound Purity

– 0.9989

SMILES

– C(=C1SC(=O)NC1=O)C2=CC(C(F)(F)F)=CC=C2

Pathway

– Apoptosis|||JAK/STAT signaling|||Chromatin/Epigenetic

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.